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产物英文名称: BIO （2’Z,3’E）-6-Bromoindirubin-3-oxime
产物中文名称: BIO （2’Z,3’E）-6-Bromoindirubin-3-oxime

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BIO 产物英文简述:
BIO （6-bromoindirubin-3'-oxime） is a specific GSK3 kinase inhibitor.  Inhibition of GSK3-beta results in activation of the canonical WNT pathway leading to the translocation of beta-catenin to the nucleus.
This chemical compound from StemRD is 98.5% pure （HPLC）.  In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolar.

Purity: Greater than 98.5% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolr.

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